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Products for NMR

 

Structural studies on large DNA and RNA molecules by nuclear magnetic resonance (NMR) require labelling of these molecules with stable isotopes.

Silantes supports your NMR studies with uniform and partially labeled biomolecules in each variation of the stable isotopes 2H, 13C and 15N. With our >98% isotopically enriched products we guarantee successful research projects with precise results.

 


Nucleosides/-tides

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Silantes offers a wide range of stable isotope labelled nucleosides and nucleotides labelled in any combination of the stable isotopes 2H, 13C and 15N for enzymatic synthesis of oligonucleotides.

Phosphoramidites

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Silantes offers a wide range of stable isotope-labelled phosphoramidites in many combinations of the stable isotopes 2H, 13C and 15N for the chemical synthesis of oligonucleotides.

Oligonucleotide Synthesis Services

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Silantes offers customised services for the synthesis of stable isotope-labelled oligonucleotides:

- Enzymatic synthesis for uniformly labelled DNA and RNA sequences

- Chemical synthesis for a nucleotide-specific labelling of DNA and RNA sequences

- Enzymatic synthesis with ribozyme for long RNA sequences

Base building blocks (A, C, G, T/U) and labelling patterns (2H, 13C, 15N) can be selected and combined as needed.

 

Cell Growth Media and Reagents

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Organisms are used for in-vivo enrichment of stable isotope labelled proteins. Silantes offers a wide range of stable isotope labelled rich growth media for E.coli and yeast for the expression of stable isotope labelled proteins. These media are optimized to ensure reproducible growth rates, cell densities and high yields of heterologous expressed protein.

Amino Acids

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Silantes offers a range of amino acids and precursors labelled in any combination of the stable isotopes 2H, 13C and 15N to purchase online. For special requests, please contact our customer service team.

NMR Standards

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Silantes offers high quality stable isotope labelled ubiquitin and ribo oligonucleotides for monitoring the performance of NMR spectrometers and for testing new pulse-sequences. 

Biomasses

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Silantes offers uniformly stable isotopically labelled biomasses such as Chlamydomonas reinhardtii, Chlorella vulgaris and Arthrospira maxima.